产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

PCBP2 Recombinant Rabbit mAb (KU)

货号: BS46827

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46827

Product Name :PCBP2 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q15366

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,FC,IP

Application_all :WB: 1:1000<br />ICC/IF: 1:100<br />FC: 1:50<br />IP: 1:20

Background :The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :35-45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HNRPE2; HNRNPE2; hnRNP-E2

Immunogen :A synthetic peptide of human PCBP2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PCBP2/hnRNP E2 in C6,3T3 cell lysates using PCBP2/hnRNP E2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）