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ALDH2 Recombinant Rabbit mAb (KU)

货号: BS46825

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46825

Product Name :ALDH2 Recombinant Rabbit mAb (KU)

Swiss-Prot :P05091

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:50<br />FC: 1:20<br />IP: 1:20

Background :This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :56 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :ALDM; ALDHI; ALDH-E2

Immunogen :A synthetic peptide of human ALDH2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of ALDH2 in K562 cell lysates using ALDH2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）