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GLCNE Recombinant Rabbit mAb (KU)

货号: BS46816

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46816

Product Name :GLCNE Recombinant Rabbit mAb (KU)

Swiss-Prot :Q9Y223

Host :Rabbit

Reactivity :Human, Rat

Applications :WB,ICC/IF,IP

Application_all :WB: 1:1000-1:5000<br />ICC/IF: 1:50<br />IP: 1:20

Background :The protein encoded by this gene is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Differential sialylation of cell surface molecules is also implicated in the tumorigenicity and metastatic behavior of malignant cells. Mutations in this gene are associated with sialuria, autosomal recessive inclusion body myopathy, and Nonaka myopathy. Alternative splicing of this gene results in transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :75 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NM; DMRV; IBM2; Uae1; GLCNE

Immunogen :A synthetic peptide of human GLCNE

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of GNE in K562,Hela cell lysates using GNE antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）