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MCM4 Recombinant Rabbit mAb (KU)

货号: BS46793

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46793

Product Name :MCM4 Recombinant Rabbit mAb (KU)

Swiss-Prot :P33991

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,FC,IP

Application_all :WB: 1:2000-1:10000<br />FC: 1:20-1:100<br />IP: 1:20

Background :The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :97 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NKCD; CDC21; CDC54; IMD54; NKGCD; hCdc21; P1-CDC21

Immunogen :A synthetic peptide of human MCM4

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MCM4 in Hela,A549,MCF-7,U251 cell lysates using MCM4 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）