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PYK2 Recombinant Rabbit mAb (KU)

货号: BS46771

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46771

Product Name :PYK2 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q14289

Host :Rabbit

Reactivity :Human, Rat

Applications :WB,IHC,IP

Application_all :WB: 1:1000<br />IHC: 1:50<br />IP: 1:20

Background :This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :116 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK

Immunogen :A synthetic peptide of human PYK2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PYK2 in A549,HL-60,U2OS cell lysates using PYK2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）