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ERCC1 Recombinant Rabbit mAb (KU)

货号: BS46765

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46765

Product Name :ERCC1 Recombinant Rabbit mAb (KU)

Swiss-Prot :P07992

Host :Rabbit

Reactivity :Human

Applications :WB,FC

Application_all :WB: 1:1000<br />FC: 1:20

Background :The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis. Multiple transcript variants encoding different isoforms have been found for this gene. The last exon of this gene overlaps with the CD3e molecule, epsilon associated protein gene on the opposite strand. [provided by RefSeq, Oct 2009]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :39 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :UV20; COFS4; RAD10

Immunogen :A synthetic peptide of human ERCC1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of ERCC1 in K562,Hela cell lysates using ERCC1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）