Product Name :Csk (phospho-S364) polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
Background :C terminal Src kinase (CSK) is a non receptor protein tyrosine kinase. One of its major functions is to specifically phosphorylate a conserved C terminal tyrosine of Src family kinases thereby down regulating their kinase activity. CSK is expressed ubiquitously as a protein of approximately 50 KDa in cytosol, but a fraction distributes to lipid rafts due to interaction with the lipid raft associated protein PAG (CSK binding protein).
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Csk (phospho-S364) polyclonal antibody detects endogenous levels of Csk protein when phosphorylated at Ser364.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL; CSK
Immunogen :Synthetic phosphopeptide derived from human Csk around the phosphorylation site of Serine 364.
Modification :Phosphorylation
