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DAB2 Recombinant Rabbit mAb (KU)

货号: BS46676

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46676

Product Name :DAB2 Recombinant Rabbit mAb (KU)

Swiss-Prot :P98082

Host :Rabbit

Reactivity :Human

Applications :WB,ICC/IF,FC,IP

Application_all :WB: 1:2000<br />ICC/IF: 1:50<br />FC: 1:20<br />IP: 1:20

Background :This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :96 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :DOC2; DOC-2

Immunogen :A synthetic peptide of human DAB2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of DAB2 in Hela,A549,HL-60,U2OS,C6 cell lysates using DAB2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）