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Cullin 5 Recombinant Rabbit mAb (KU)

货号: BS46665

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46665

Product Name :Cullin 5 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q93034

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB: 1:1000-1:5000

Background :Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :91 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CUL-5; VACM1; VACM-1

Immunogen :Recombinant protein of human Cullin 5

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Cullin 5/CUL-5 in C6,3T3,Hela cell lysates using Cullin 5/CUL-5 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）