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FEN1 Recombinant Rabbit mAb (KU)

货号: BS46637

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46637

Product Name :FEN1 Recombinant Rabbit mAb (KU)

Swiss-Prot :P39748

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC

Application_all :WB: 1:1000<br />IHC: 1:50-1:200

Background :The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MF1; RAD2; FEN-1

Immunogen :A synthetic peptide of human FEN1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of FEN1 in Hela,MCF-7,U251,HL-60 using FEN1 antibody(1:1000 diluted)

免疫沉淀（IP）

免疫组织化学（IHC）