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PEN2 Recombinant Rabbit mAb (KU)

货号: BS46632

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46632

Product Name :PEN2 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q9NZ42

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF,FC

Application_all :WB: 1:1000<br />IHC: 1:50<br />ICC/IF: 1:50<br />FC: 1:20-1:100

Background :Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :12 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PEN2; PEN-2; MDS033; ACNINV2; MSTP064

Immunogen :A synthetic peptide of human PEN2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PEN2 in Hela,A549HL-60,C6 using PEN2 antibody(1:1000 diluted)

免疫沉淀（IP）

免疫组织化学（IHC）