产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

PKR Recombinant Rabbit mAb (KU)

货号: BS46591

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46591

Product Name :PKR Recombinant Rabbit mAb (KU)

Swiss-Prot :Q03963

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,FC,IP

Application_all :WB: 1:1000<br />ICC/IF: 1:20<br />FC: 1:20<br />IP: 1:20

Background :IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA and RNA viruses including west nile virus (WNV), sindbis virus (SV), foot-and-mouth virus (FMDV), semliki Forest virus (SFV) and lymphocytic choriomeningitis virus (LCMV). Inhibits viral replication via phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (EIF2S1), this phosphorylation impairs the recycling of EIF2S1 between successive rounds of initiation leading to inhibition of translation which eventually results in shutdown of cellular and viral protein synthesis.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :74 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Pkr; Tik; Prkr; AI467567; AI747578; 2310047A08Rik; 4732414G15Rik

Immunogen :Recombinant protein of mouse PKR

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PKR in C6,3T3 cell lysates using PKR antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）