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HSD17B1 Recombinant Rabbit mAb (KU)

货号: BS46582

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46582

Product Name :HSD17B1 Recombinant Rabbit mAb (KU)

Swiss-Prot :P14061

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:2000-1:10000<br />IHC: 1:20-1:100<br />ICC/IF: 1:20-1:100<br />FC: 1:50<br />IP: 1:20

Background :This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :E2DH; HSD17; EDHB17; EDH17B2; SDR28C1; 17-beta-HSD; 20-alpha-HSD

Immunogen :A synthetic peptide of human HSD17B1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of HSD17B1 in human placenta cell lysates using HSD17B1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）