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Cadherin 10 Recombinant Rabbit mAb (KU)

货号: BS46567

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46567

Product Name :Cadherin 10 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q9Y6N8

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,FC

Application_all :WB: 1:1000<br />FC: 1:20

Background :This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. Mutations in this gene may be associated with lung squamous cell carcinoma and colorectal cancer in human patients. [provided by RefSeq, Nov 2015]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :110 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :T2-cadherin; CDH10

Immunogen :A synthetic peptide of human cadherin 10

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of cadherin 10 in U2OS,C6 using cadherin 10 antibody(1:1000 diluted)

免疫沉淀（IP）

免疫组织化学（IHC）