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RAP1GAP Recombinant Rabbit mAb (KU)

货号: BS46546

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46546

Product Name :RAP1GAP Recombinant Rabbit mAb (KU)

Swiss-Prot :P47736

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,ICC/IF,FC,IP

Application_all :WB: 1:1000-1:5000<br />ICC/IF: 1:20-1:50<br />FC: 1:20<br />IP: 1:20

Background :This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :95 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RAPGAP; RAP1GA1; RAP1GAP1; RAP1GAPII

Immunogen :A synthetic peptide of human RAP1GAP

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of RAP1GAP in C6,3T3 cell lysates using RAP1GAP antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）