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PAR4 Recombinant Rabbit mAb (KU)

货号: BS46483

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46483

Product Name :PAR4 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q96IZ0

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IP

Application_all :WB: 1:2000-1:10000<br />IP: 1:20

Background :This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :41 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PAR4; Par-4

Immunogen :A synthetic peptide of human PAR4

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PAR4 in Hela,A549,HL-60,U251,U87-MG cell lysates using PAR4 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）