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MAPKAP Kinase 3 Recombinant Rabbit mAb (KU)

货号: BS46472

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46472

Product Name :MAPKAP Kinase 3 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q16644

Host :Rabbit

Reactivity :Human

Applications :WB,FC,IP

Application_all :WB: 1:2000-1:10000<br />FC: 1:20<br />IP: 1:20

Background :This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :3PK; MK3; MK-3; MDPT3; MAPKAP3; MAPKAP-K3; MAPKAPK-3

Immunogen :A synthetic peptide of human MK-3

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MK-3 in A549,HL-60 cell lysates using MK-3 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）