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MSH6 Recombinant Rabbit mAb (KU)

货号: BS46422

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46422

Product Name :MSH6 Recombinant Rabbit mAb (KU)

Swiss-Prot :P52701

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:1000<br />IHC: 1:200<br />ICC/IF: 1:20<br />FC: 1:100<br />IP: 1:20

Background :This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :163 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GTBP; HSAP; p160; GTMBP; HNPCC5

Immunogen :A synthetic peptide of human MSH6

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MSH6 in A549,MCF-7,U251,C2C12 cell lysates using MSH6 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）