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SF3B3 Recombinant Rabbit mAb (KU)

货号: BS46372

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46372

Product Name :SF3B3 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q15393

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF,FC

Application_all :WB: 1:1000<br />IHC: 1:500<br />ICC/IF: 1:50<br />FC: 1:50

Background :This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :136 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :RSE1; SAP130; SF3b130; STAF130

Immunogen :A synthetic peptide of human SF3B3

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of SF3B3 in SHSY-5Y,C6 cell lysates using SF3B3 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）