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Importin 9 Recombinant Rabbit mAb (KU)

货号: BS46324

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46324

Product Name :Importin 9 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q96P70

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:50<br />FC: 1:50<br />IP: 1:20

Background :Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :115 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Imp9

Immunogen :A synthetic peptide of human Importin 9

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Importin 9/RANBP9 in Jurkat,Hela cell lysates using Importin 9/RANBP9(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）