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EWSR1 Recombinant Rabbit mAb (KU)

货号: BS46323

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46323

Product Name :EWSR1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q01844

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:2000-1:10000<br />IHC: 1:50-1:200<br />ICC/IF: 1:50-1:200

Background :This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :EWS; EWS-FLI1; bK984G1.4

Immunogen :A synthetic peptide of human EWSR1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of EWSR1 in MCF7,3T3,Hela cell lysates using EWSR1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）