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Activin Receptor Type IA Recombinant Rabbit mAb (KU)

货号: BS46310

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46310

Product Name :Activin Receptor Type IA Recombinant Rabbit mAb (KU)

Swiss-Prot :Q04771

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IP

Application_all :WB: 1:1000-1:5000<br />IP: 1:20

Background :Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FOP; ALK2; SKR1; TSRI; ACTRI; ACVR1A; ACVRLK2

Immunogen :A synthetic peptide of human Activin Receptor Type IA

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Activin Receptor Type IA in Hela cell lysates using Activin Receptor Type IA antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）