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Syntrophin alpha 1 Recombinant Rabbit mAb (KU)

货号: BS46275

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46275

Product Name :Syntrophin alpha 1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q13424

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC,ICC/IF,FC

Application_all :WB: 1:1000-1:5000<br />IHC: 1:50<br />ICC/IF: 1:50<br />FC: 1:50

Background :Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :54 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :SNT1; LQT12; TACIP1; dJ1187J4.5

Immunogen :A synthetic peptide of human Syntrophin alpha 1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Syntrophin alpha 1 in K562 cell lysates using Syntrophin alpha 1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）