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GNB3 Recombinant Rabbit mAb (KU)

货号: BS46251

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS46251

Product Name :GNB3 Recombinant Rabbit mAb (KU)

Swiss-Prot :P16520

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC

Application_all :WB: 1:1000<br />IHC: 1:20

Background :Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit which belongs to the WD repeat G protein beta family. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity. This polymorphism is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2014]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :37 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CSNB1H

Immunogen :A synthetic peptide of human GNB3

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of GNB3 in C6,Rat Brain,MCF7 cell lysates using GNB3 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）