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Cyclin H Recombinant Rabbit mAb (KU)

货号: BS46195

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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详细信息检测数据实验指南文献

No. :BS46195

Product Name :Cyclin H Recombinant Rabbit mAb (KU)

Swiss-Prot :P51946

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB: 1:1000-1:5000

Background :The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CAK; p34; p37; CycH

Immunogen :A synthetic peptide of human Cyclin H

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Cyclin H in Jurkat cell lysates using Cyclin H antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）