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MTH1 Recombinant Rabbit mAb (KU)

货号: BS46157

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46157

Product Name :MTH1 Recombinant Rabbit mAb (KU)

Swiss-Prot :P36639

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF,FC

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:50<br />FC: 1:20

Background :Misincorporation of oxidized nucleoside triphosphates into DNA/RNA during replication and transcription can cause mutations that may result in carcinogenesis or neurodegeneration. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation. The encoded protein is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. Several alternatively spliced transcript variants, some of which encode distinct isoforms, have been identified. Additional variants have been observed, but their full-length natures have not been determined. A single-nucleotide polymorphism that results in the production of an additional, longer isoform (p26) has been described. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :18 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :MTH1

Immunogen :Recombinant protein of human MTH1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MTH1 in K562 cell lysates using MTH1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）