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Legumain Recombinant Rabbit mAb (KU)

货号: BS46145

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46145

Product Name :Legumain Recombinant Rabbit mAb (KU)

Swiss-Prot :Q99538

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB

Application_all :WB: 1:2000-1:10000

Background :This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :56,46,37 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AEP; LGMN1; PRSC1

Immunogen :Recombinant protein of human Legumain

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Legumain in Jurkat,Hela cell lysates using Legumain antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）