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CDC42 Recombinant Rabbit mAb (KU)

货号: BS46045

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS46045

Product Name :CDC42 Recombinant Rabbit mAb (KU)

Swiss-Prot :P60953

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:2000-1:20000<br />IHC: 1:100-1:200<br />ICC/IF: 1:200-1:500<br />FC: 1:100<br />IP: 1:20

Background :The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. [provided by RefSeq, Apr 2013]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :21 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :TKS; G25K; CDC42Hs

Immunogen :Recombinant protein of human CDC42

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of CDC42 in C6,Hela cell lysates using CDC42 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）