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Cystatin B Recombinant Rabbit mAb (KU)

货号: BS45993

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45993

Product Name :Cystatin B Recombinant Rabbit mAb (KU)

Swiss-Prot :P04080

Host :Rabbit

Reactivity :Human, Rat

Applications :WB,IHC

Application_all :WB: 1:1000-1:5000<br />IHC: 1:100-1:200

Background :The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies. [provided by RefSeq, Jul 2016]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :11 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PME; ULD; CST6; EPM1; STFB; CPI-B; EPM1A

Immunogen :A synthetic peptide of human Cystatin-B

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Cystatin-B in Hela,A549,HL-60 using Cystatin-B antibody(1:1000 diluted)

免疫沉淀（IP）

免疫组织化学（IHC）