产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

FKBP4 Recombinant Rabbit mAb (KU)

货号: BS45806

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45806

Product Name :FKBP4 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q02790

Host :Rabbit

Reactivity :Human

Applications :WB, ICC/IF, FC, IP

Application_all :WB: 1:1000<br />ICC/IF: 1:100<br />FC: 1:200<br />IP: 1:20

Background :The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq, Sep 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :HBI; p52; Hsp56; FKBP51; FKBP52; FKBP59; PPIase

Immunogen :Recombinant protein of human FKBP4

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts from HeLa cells using db12312 at 1:1000.

免疫沉淀（IP）

免疫组织化学（IHC）