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Cathepsin S Recombinant Rabbit mAb (KU)

货号: BS45719

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45719

Product Name :Cathepsin S Recombinant Rabbit mAb (KU)

Swiss-Prot :P25774

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:100<br />ICC/IF: 1:20-1:100

Background :The preproprotein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that participates in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The mature protein cleaves the invariant chain of MHC class II molecules in endolysosomal compartments and enables the formation of antigen-MHC class II complexes and the proper display of extracellular antigenic peptides by MHC-II. The mature protein also functions as an elastase over a broad pH range. When secreted from cells, this protein can remodel components of the extracellular matrix such as elastin, collagen, and fibronectin. This gene is implicated in the pathology of many inflammatory and autoimmune diseases and, given its elastase activity, plays a significant role in some pulmonary diseases. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2020]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CTSS

Immunogen :A synthetic peptide of human Cathepsin S

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts from U87-MG cells using db13417 at 1:1000.

免疫沉淀（IP）

免疫组织化学（IHC）