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Myosin，smooth muscle heavy chain 1 and 2 Recombinant Rabbit mAb (KU)

货号: BS45696

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS45696

Product Name :Myosin，smooth muscle heavy chain 1 and 2 Recombinant Rabbit mAb (KU)

Swiss-Prot :P35749

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC

Application_all :WB: 1:2000-1:10000<br />IHC: 1:20-1:100

Background :The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :227 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AAT4; FAA4; SMHC; SMMHC

Immunogen :A synthetic peptide of human Myosin，smooth muscle heavy chain 1 and 2

Conjugate :Unconjugated

Modification :Unmodification

Western blot analysis of extracts from Mouse spleen tissue using db13688 at 1:1000.

免疫沉淀（IP）

免疫组织化学（IHC）