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alpha Actinin 4 Recombinant Rabbit mAb (KU)

货号: BS45594

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45594

Product Name :alpha Actinin 4 Recombinant Rabbit mAb (KU)

Swiss-Prot :O43707

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:1000-1:5000<br />IHC: 1:20-1:100<br />ICC/IF: 1:20-1:50<br />FC: 1:20<br />IP: 1:20-1:50

Background :Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :105 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :FSGS; FSGS1; ACTININ-4

Immunogen :A synthetic peptide of human alpha Actinin 4

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of alpha Actinin 4 in K562,Rat Brain,C6,3T3,Hela cell lysates using alpha Actinin 4 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）