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APC Recombinant Rabbit mAb (KU)

货号: BS45585

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45585

Product Name :APC Recombinant Rabbit mAb (KU)

Swiss-Prot :P25054

Host :Rabbit

Reactivity :Human, Rat

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:20<br />FC: 1:20<br />IP: 1:20

Background :This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :160 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46

Immunogen :A synthetic peptide of human APC

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of APC in Hela,A549,HL-60,U2OS cell lysates using APC antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）