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Axin 2 Recombinant Rabbit mAb (KU)

货号: BS45560

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45560

Product Name :Axin 2 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q9Y2T1

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:20

Background :The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and conductin, which leads to the degradation of beta-catenin. Apparently, the deregulation of beta-catenin is an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :94 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :AXIL; ODCRCS

Immunogen :A synthetic peptide of human Axin 2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Axin 2 in K562,C6,3T3,Hela cell lysates using Axin 2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）