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cAMP Protein Kinase Catalytic subunit Recombinant Rabbit mAb (KU)

货号: BS45542
价格 1200
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS45542
Product Name :cAMP Protein Kinase Catalytic subunit Recombinant Rabbit mAb (KU)
Swiss-Prot :P17612
Host :Rabbit
Reactivity :Human, Mouse, Rat
Applications :WB,IHC,ICC/IF,FC,IP
Application_all :WB: 1:2000-1:20000<br />IHC: 1:200-1:500<br />ICC/IF: 1:100-1:200<br />FC: 1:50<br />IP: 1:50
Background :This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms. [provided by RefSeq, Jan 2015]
Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Purification&Purity :Affinity Purification
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :IgG
BiowMW :41 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PKACA; PPNAD4
Immunogen :A synthetic peptide of human cAMP Protein Kinase Catalytic subunit
Conjugate :Unconjugated
Modification :Unmodification
Western blot detection of cAMP Protein Kinase Catalytic subunit in K562,C6,3T3,Hela cell lysates using cAMP Protein Kinase Catalytic subunit antibody(1:1000 diluted).

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400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com