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CDK4 Recombinant Rabbit mAb (KU)

货号: BS45518

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45518

Product Name :CDK4 Recombinant Rabbit mAb (KU)

Swiss-Prot :P11802

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC,ICC/IF,IP

Application_all :WB: 1:1000<br />IHC: 1:50<br />ICC/IF: 1:50<br />IP: 1:20

Background :The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :34 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CMM3; PSK-J3

Immunogen :Recombinant protein of human Cdk4

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Cdk4 in K562,C6,3T3,Hela cell lysates using Cdk4 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）