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Glucocorticoid Receptor Recombinant Rabbit mAb (KU)

货号: BS45446

价格：￥ 1200

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS45446

Product Name :Glucocorticoid Receptor Recombinant Rabbit mAb (KU)

Swiss-Prot :P06537

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC

Application_all :WB: 1:1000<br />IHC: 1:500-1:2000<br />ICC/IF: 1:200-1:500<br />FC: 1:200-1:500

Background :This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms. Additional isoforms resulting from the use of alternate in-frame translation initiation sites have also been described, and shown to be functional, displaying diverse cytoplasm-to-nucleus trafficking patterns and distinct transcriptional activities (PMID:15866175). [provided by RefSeq, Feb 2011]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :94,91 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :GR; GCR; GRL; GCCR; GCRST

Immunogen :Recombinant protein of mouse Glucocorticoid Receptor

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Glucocorticoid Receptor in K562,3T3,Hela cell lysates using Glucocorticoid Receptor antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）