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HMGCR Recombinant Rabbit mAb (KU)

货号: BS45414

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45414

Product Name :HMGCR Recombinant Rabbit mAb (KU)

Swiss-Prot :P04035

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IP

Application_all :WB: 1:1000<br />IP: 1:20

Background :HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :98 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :LDLCQ3

Immunogen :A synthetic peptide of human HMGCR

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of HMGCR in K562,3T3,Hela cell lysates using HMGCR antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）