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LRP1 Recombinant Rabbit mAb (KU)

货号: BS45356

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45356

Product Name :LRP1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q07954

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:2000-1:20000<br />IHC: 1:50<br />ICC/IF: 1:100<br />FC: 1:100<br />IP: 1:20

Background :This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :85 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :APR; KPA; LRP; A2MR; CD91; APOER; LRP1A; TGFBR5; IGFBP3R

Immunogen :A synthetic peptide of human LRP1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of LRP1 in Rat Brain,C6 cell lysates using LRP1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）