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MEK2 Recombinant Rabbit mAb (KU)

货号: BS45346

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45346

Product Name :MEK2 Recombinant Rabbit mAb (KU)

Swiss-Prot :P36507

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB,IHC,ICC/IF,FC,IP

Application_all :WB: 1:2000<br />IHC: 1:20<br />ICC/IF: 1:20<br />FC: 1:20<br />IP: 1:20

Background :The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CFC4; MEK2; MKK2; MAPKK2; PRKMK2

Immunogen :A synthetic peptide of human MEK2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MEK2 in Hela,A549 cell lysates using MEK2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）