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MLKL Recombinant Rabbit mAb (KU)

货号: BS45339

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45339

Product Name :MLKL Recombinant Rabbit mAb (KU)

Swiss-Prot :Q8NB16

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:200-1:500<br />ICC/IF: 1:200

Background :This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :hMLKL

Immunogen :Recombinant protein of human MLKL

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of MLKL in U251MG,Hela cell lysates using MLKL antibody(1:500 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）