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NEDD8 Recombinant Rabbit mAb (KU)

货号: BS45319

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45319

Product Name :NEDD8 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q15843

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC, IP

Background :Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.