Product Name :Occludin Recombinant Rabbit mAb (KU)
Swiss-Prot :Q16625, Q61146, Q6P6T5
Reactivity :Human, Mouse, Rat
Applications :WB, IHC, ICC/IF, FC, IP
Background :This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011]
