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PABPN1 Recombinant Rabbit mAb (KU)

货号: BS45293

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45293

Product Name :PABPN1 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q86U42

Host :Rabbit

Reactivity :Human, Mouse

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:1000-1:5000<br />IHC: 1:20-1:100<br />ICC/IF: 1:20-1:50<br />FC: 1:20<br />IP: 1:20

Background :This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :OPMD; PAB2; PABII; PABP2; PABP-2

Immunogen :A synthetic peptide of human PABPN1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of PABPN1 in Jurkat,Hela,COS7,Raji cell lysates using PABPN1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）