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Pyruvate Dehydrogenase E1 alpha Recombinant Rabbit mAb (KU)

货号: BS45250

价格：￥ 1200

货期：现货（1-2个工作日）

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No. :BS45250

Product Name :Pyruvate Dehydrogenase E1 alpha Recombinant Rabbit mAb (KU)

Swiss-Prot :P08559

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF, FC, IP

Application_all :WB: 1:1000-1:2000<br />IHC: 1:20-1:100<br />ICC/IF: 1:20-1:100<br />FC: 1:20<br />IP: 1:20-1:50

Background :The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PDHA; PDHAD; PHE1A; PDHCE1A

Immunogen :A synthetic peptide of human Pyruvate Dehydrogenase E1-alpha subunit

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Pyruvate Dehydrogenase E1-alpha subunit in C6,3T3 cell lysates using Pyruvate Dehydrogenase E1-alpha subunit antibody(1:1000 diluted).