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Rad50 Recombinant Rabbit mAb (KU)

货号: BS45244

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45244

Product Name :Rad50 Recombinant Rabbit mAb (KU)

Swiss-Prot :Q92878

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB,IHC

Application_all :WB: 1:1000<br />IHC: 1:500-1:2000

Background :The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :154 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NBSLD; RAD502; hRad50

Immunogen :Recombinant protein of human Rad50

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Rad50 in Hela,A549,HL-60 using Rad50 antibody(1:1000 diluted)

免疫沉淀（IP）

免疫组织化学（IHC）