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Raf1 Recombinant Rabbit mAb (KU)

货号: BS45241

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45241

Product Name :Raf1 Recombinant Rabbit mAb (KU)

Swiss-Prot :P04049

Host :Rabbit

Reactivity :Human

Applications :WB,IHC,ICC/IF

Application_all :WB: 1:1000<br />IHC: 1:20<br />ICC/IF: 1:20

Background :This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :73 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :NS5; CRAF; Raf-1; c-Raf; CMD1NN

Immunogen :A synthetic peptide of human Raf1

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of Raf1 in C6,3T3,Hela cell lysates using Raf1 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）