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SFPQ Recombinant Rabbit mAb (KU)

货号: BS45213

价格：￥ 1200

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45213

Product Name :SFPQ Recombinant Rabbit mAb (KU)

Swiss-Prot :P23246

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB, IHC, ICC/IF

Application_all :WB: 1:2000-1:10000<br />IHC: 1:50<br />ICC/IF: 1:20

Background :DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. During splicing of PTPRC/CD45, a phosphorylated form is sequestered by THRAP3 from the pre-mRNA in resting T-cells; T-cell activation and subsequent reduced phosphorylation is proposed to lead to release from THRAP3 allowing binding to pre-mRNA splicing regulatotry elements which represses exon inclusion.

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :100 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PSF; POMP100; PPP1R140

Immunogen :A synthetic peptide of human SFPQ

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of SFPQ in K562,Rat Brain,C6,3T3,Hela cell lysates using SFPQ antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）