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SOCS2 Recombinant Rabbit mAb (KU)

货号: BS45203

价格：￥ 1200

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS45203

Product Name :SOCS2 Recombinant Rabbit mAb (KU)

Swiss-Prot :O14508

Host :Rabbit

Reactivity :Human

Applications :WB,ICC/IF,IP

Application_all :WB: 1:1000-1:5000<br />ICC/IF: 1:20-1:50<br />IP: 1:20-1:50

Background :This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Product :Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification&Purity :Affinity Purification

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :IgG

BiowMW :22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2

Immunogen :A synthetic peptide of human SOCS2

Conjugate :Unconjugated

Modification :Unmodification

Western blot detection of SOCS2 in K562 cell lysates using SOCS2 antibody(1:1000 diluted).

免疫沉淀（IP）

免疫组织化学（IHC）